Prospective Anticancer Efficacy of Bioactive Compounds from Chicoreus ramosus (Linnaeus, 1758)
1, 1, 1
- 1Department of Zoology, St. Mary’s College (Autonomous) Thoothukudi, Affliated to Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli, Tamil Nadu, INDIA.
CORRESPONDENCE
P.Kaviya Priya
Department of Zoology, St. Mary’s College (Autonomous) Thoothukudi, Affliated to Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli, Tamil Nadu, INDIA.
Received: 05-06-2023; Revised: 18-08-2023; Accepted: 14-09-2023.
Volume 12, Issue 2 · pp. 402-407 · 2023 · DOI: 10.5530/ajbls.2023.12.53
ABSTRACT
Aim: For over three decades, marine creatures have been a rich source of novel chemical compounds that have accelerated the development of marine natural product chemistry. Among the marine organisms, molluscs are one of the most successful forms of beast life, and they’ve conquered nearly every niche and live in all the abysses. In the present study, the marine gastropod Chicoreus ramosus has been selected with a view to screen the bioactive compounds responsible for biological activities.Materials and Methods: The cytotoxic effects of the experimental organism were performed using an MTT assay on the HeLa cell line. The chance of cell viability was set up to be dropped by adding attention to the samples.Results: The result of GC-MS results showed 10 compounds responsible for antioxidant and anticancer activities. The results of the present study revealed that Chicoreus ramosus showed potent cytotoxic activities against HeLa cell lines with IC50 values of 218.60 µg/mL.Conclusion: Methanolic extract of Chicoreus ramosus yielded a pool of bioactive compounds which are responsible for anticancer activity. Thus, it may be helpful to the pharmacological technologist for the extraction of anticancer drugs in the near future.
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Priya, P., Subavathy, P., & Dominikal, A. M. A. (2023). Prospective Anticancer Efficacy of Bioactive Compounds from Chicoreus ramosus (Linnaeus, 1758). Asian Journal of Biological and Life Sciences, 12(2), 402-407. https://doi.org/10.5530/ajbls.2023.12.53
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