Studies on in vitro Anti-Diabetic Activities of the Epigeic Earthworm, Eisenia fetida Extract
1, 1
- 1Department of Zoology, Karnatak University, Dharwad, Karnataka, INDIA.
CORRESPONDENCE
Pulikeshi M. Biradar
Department of Zoology, Karnatak University, Dharwad, Karnataka, INDIA.
Received: 11-05-2024; Revised: 14-07-2024; Accepted: 18-08-2024.
Volume 13, Issue 2 · pp. 316-321 · 2024 · DOI: 10.5530/ajbls.2024.13.40
ABSTRACT
Aim: Diabetes is considered as one of the serious complications and disorders in recent years. So, the present work was undertaken to investigate the anti-diabetic activity using Eisenia fetida earthworm extract.Materials and Methods: The anti-diabetic activity was carried out by using different concentrations of earthworm, Eisenia fetida extract with two different methods: alpha-amylase inhibitory assay and glucose uptake assay, by using standard drugs Metformin and Metronidazole, respectively.Results: Results revealed that the earthworm, Eisenia fetida extract exhibits anti-diabetic activity by inhibiting alpha-amylase activity and also by increasing the glucose uptake in the cells. Thus, Eisenia fetida earthworm extract may serve as an alternative anti-diabetic drug to prevent diabetic complications in the near future.
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Shetty, A., & Biradar, P. M. (2024). Studies on in vitro Anti-Diabetic Activities of the Epigeic Earthworm, Eisenia fetida Extract. Asian Journal of Biological and Life Sciences, 13(2), 316-321. https://doi.org/10.5530/ajbls.2024.13.40
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