Double Chromosomal Anomalies in Turner Syndrome: Rare Co-existence of Robertsonian Translocation with Monosomy X and Isochromosome XQ
1, 1
- 1Department of Genetics, Thyrocare Technologies Limited, Plot No.D37/1, TTC Industrial area, MIDC, Turbhe, Navi Mumbai, Maharashtra, INDIA.
CORRESPONDENCE
Sandhya Iyer
Department of Genetics, Thyrocare Technologies Limited, Plot No.D37/1, TTC Industrial area, MIDC, Turbhe, Navi Mumbai, Maharashtra, INDIA.
Received: 17-09-2020; Accepted: 02-12-2020.
Volume 9, Issue 3 · pp. 421-423 · 2021 · DOI: 10.5530/ajbls.2020.9.64
ABSTRACT
Background and Aim: The co-existence of a Robertsonian translocation with Turner Syndrome (TS) or a variant of Turner Syndrome (isochromosome Xq) is an uncommon phenomenon. In this report, we present two cases with double chromosomal anomalies. Case Report: In the first case, we present findings from a 19-year-old female, detected to harbor classic TS combined with t(13;14) Robertsonian translocation. The second case involves a 13-year-old female, with isochromosome Xq10 (a known variant of Turner Syndrome) combined with t(13;14) Robertsonian translocation.Conclusion: Literature around double chromosome anomalies was found to be scarce, and our case report is one of the first few to identify a structural abnormality of the X chromosome (isochromosome X) along with a t(13;14) Robertsonian translocation.
KEYWORDS
REFERENCES
As publishedShowing references and in-text citations exactly as published.
Cite this article
SELECT FORMAT
Sinkar, P., & Iyer, S. (2021). Double Chromosomal Anomalies in Turner Syndrome: Rare Co-existence of Robertsonian Translocation with Monosomy X and Isochromosome XQ. Asian Journal of Biological and Life Sciences, 9(3), 421-423. https://doi.org/10.5530/ajbls.2020.9.64
Copyright and licence
© 2021 Author(s)
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0