Incidental Detection of HbQ-India during Beta-Thalassemia Screening
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- 1Hematology Division, Thyrocare Technologies Limited, Plot No.D37/1,TTC Industrial area, MIDC, Turbhe, Navi Mumbai - 400703, INDIA.
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Sandhya Iyer
Hematology Division, Thyrocare Technologies Limited, Plot No.D37/1,TTC Industrial area, MIDC, Turbhe, Navi Mumbai - 400703, INDIA.
Received: 15-01-2015; Accepted: 20-03-2015.
Volume 4, Issue 1 · pp. 20-25 · 2015 · DOI:
ABSTRACT
HbQ-India is a relatively rare hemoglobin variant seen particularly in the Indian subcontinent. In this report we present twenty cases of HbQ-India variant and two cases of HbQ India/Beta- Thalassemia detected in our lab during thalassemia screening tests conducted in camps along with family studies of few cases. These cases were detected over a span of three months from samples screened for thalassemia. In order to perform familial studies, sample of family members of six cases were collected totaling to twenty-two affected cases. Molecular confirmation of the detected HbQ-India trait was done using PCR-ARMS technology. Our study detected frequency of HbQ-India carriers at 1.47%.
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Iyer, S., Sakhare, S., Sengupta, C., & Velumani, A. (2015). Incidental Detection of HbQ-India during Beta-Thalassemia Screening. Asian Journal of Biological and Life Sciences, 4(1), 20-25.
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