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Anti-Inflammatory Activity of Seeds of Prosopis spicigera in Animals

1, 3, 2, 1

  1. 1Dept. of Chemistry, D.B.S. (P.G.) College, Kanpur-208006 Uttar Pradesh, INDIA.
  2. 2Dept. of Micro-biology, D.B.S. (P.G.) College, Kanpur-06 Uttar Pradesh, INDIA.
  3. 3Dept. of Chemistry, D.V. (P.G.) College, Orai-285001 Uttar Pradesh, INDIA.

CORRESPONDENCE

Rajiv Agrawal

Dept. of Chemistry, D.B.S. (P.G.) College, Kanpur-208006 Uttar Pradesh, INDIA.

dr.rajivagrawal@gmail.com

Received: 25-05-2013; Accepted: 01-07-2013.

Volume 2, Issue 2 · pp. 119-121 · 2013 · DOI:

ABSTRACT

Prosopis spicigera Sm. (Leguminasae) is a commonly used plant in Indian traditional medicine. In the current study anti-inflammatory activity of ethanolic extract of P. spicigera Seeds was investigated using different animal models. The extract was also subjected to phyto-chemical analysis and their toxic potential. The anti-inflammatory activity was measured using the carrageenan-induced paw edema test. The air dried seeds of P.spicigera were soaked in ethanol (1:4, w/v) at the temperature of 60oC for 72 h. The supernatant collected was evaporated under reduced pressure and kept at 5oC until used. The extract was emulsified using 0.1% Tween -80 in normal Saline to prepare the doses of 33, 100 and 300 mg kg -1 , before performing each experiment. Anti-inflammatory activity in a dose-dependant manner in all assays used to the extract administered intraperitoneally exhibited significant (p<0.05).

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    Agrawal, R., Garg, H. K., Garg, U., & Singh, S. (2013). Anti-Inflammatory Activity of Seeds of Prosopis spicigera in Animals. Asian Journal of Biological and Life Sciences, 2(2), 119-121.

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    © 2013 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0