Beyond Seizures: Exploring Cannabidiol in Dravet Syndrome
1, 1, 1, 1, 1, 1
- 1Department of Pharmacy Practice, Al Shifa College of Pharmacy, Perinthalmanna, Malappuram, Kerala, INDIA.
CORRESPONDENCE
Sai Keerthana Puthiyedath Cheruvatta
Department of Pharmacy Practice, Al Shifa College of Pharmacy, Perinthalmanna, Malappuram, Kerala, INDIA.
Received: 04-10-2024; Revised: 16-11-2024; Accepted: 17-12-2024.
Volume 13, Issue 3 · pp. 885-889 · 2024 · DOI: 10.5530/ajbls.2024.13.106
ABSTRACT
Aim: Dravet Syndrome (DS) is a severe epileptic and developmental encephalopathy causing drug-resistant seizures and developmental delay; this report presents two infant cases and evaluates CBD as adjunct therapy.Materials and Methods: Clinical case details, genetic testing (SCN1A) and treatment response were recorded and monitored.Results: Cannabidiol (CBD) added to regimens provided improved seizure control in refractory cases, with noted adverse effects including somnolence and GI upset.Conclusion: CBD may be beneficial for seizure control in DS but requires careful monitoring and further research on pediatric dosing.
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Simon, P., Rajagopalan, N. S., Jahnas, F., Sudheer, F., Pattambi, M. A., & Cheruvatta, S. K. P. (2024). Beyond Seizures: Exploring Cannabidiol in Dravet Syndrome. Asian Journal of Biological and Life Sciences, 13(3), 885-889. https://doi.org/10.5530/ajbls.2024.13.106
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This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. CC BY 4.0