Article · Volume 13, Issue 2 · pp. 322-329

Antidiabetic and Antimicrobial Properties of Leaf and Bark Extracts of Cerbera odollam

Sonia Angeline Martin¹, Esther Shoba¹, Suchithra Jayakumar¹, Muhammed Asharudheen¹

¹Department of Life Sciences, Kristu Jayanti College, K. Narayanapura, Kothanur, Bangalore, Karnataka, INDIA.

Abstract

Aim: The study aimed to identify the phytochemical components, antibacterial, antifungal, and antidiabetic activity in methanol and aqueous extracts of Cerbera odollam leaves and bark using different testing techniques.Materials and Methods: This research work evaluated the antibacterial and anti-diabetic effects of methanol and aqueous extracts of Cerbera odollam; extracts were generated by drying and extracting the leaf and bark using a Soxhlet apparatus. The antibacterial and antifungal activity was determined using the well diffusion method.Results: The antidiabetic role of the plant extracts was analyzed using an alpha-amylase inhibition screening assay followed by a starch iodine assay. The results were validated with UV-VIS Spectroscopy and FTIR analysis. The methanolic extract of the leaf possesses maximum antibacterial, antifungal, and antidiabetic activity.Conclusion: This study provides new insights and scope to analyze the methanol and aqueous bark extracts of Cerbera odollam for their effective antidiabetic activity.

Keywords: Antidiabetic; Antimicrobial; Cerbera odollam; FTIR; Phytochemicals.

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